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  • Téma összefoglaló
    Utoljára frissítve: 2021-10-10 15:19

    PROHARDVER!

    Ez egy agyalós-beszélgetős Covid-19 topik. Érvelni kötelező, a másikkal foglalkozni tilos, rettegőzés duplán, a szemlélet tudományos (a "meddig maradjanak a lezárások", azaz a társadalmi rész elfér, de csak szűken/járványhoz kapcsolódóan), ergo nem oltásellenes, nem hit alapú. Ami ebben a szellemben íródik, marad, ami nem, az nem, téríteni meg se próbálj.

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    Ivermectin for preventing and treating COVID‐19

    What did we do?
    We searched for randomized controlled trials that investigated ivermectin to prevent or treat COVID‐19 in humans. People being treated with ivermectin had to have laboratory‐test confirmed COVID‐19 and be receiving treatment in hospital or as outpatients.
    We compared and summarized the results of the studies and rated our confidence in the evidence, based on common criteria as to how reliable the evidence is.

    What did we find?
    We found 14 studies with 1678 participants that investigated ivermectin compared to no treatment, placebo, or usual care.
    For treatment, there were nine studies of people with moderate COVID‐19 in hospital and four of outpatients with mild COVID‐19. The studies used different doses of ivermectin and different durations of treatment.
    One study investigated ivermectin to prevent COVID‐19.
    We also found 31 ongoing studies, and there are 18 studies still requiring clarification from the authors or not yet published.

    What are the limitations of the evidence?
    Our confidence in the evidence is very low because we could only include 14 studies with few participants and few events, such as deaths or need for ventilation. The methods differed between studies, and they did not report everything we were interested in, such as quality of life.

    How up to date is this evidence?
    The evidence is up to date to 26 May 2021.

    ->>>
    Authors' conclusions
    Based on the current very low‐ to low‐certainty evidence, we are uncertain about the efficacy and safety of ivermectin used to treat or prevent COVID‐19. The completed studies are small and few are considered high quality. Several studies are underway that may produce clearer answers in review updates. Overall, the reliable evidence available does not support the use ivermectin for treatment or prevention of COVID‐19 outside of well‐designed randomized trials.

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