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• #105311 Ringman nagyúr radi8tor #105307

  Új Válasz 2021-06-27 20:53:05 #105311

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  Ringman

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  válasz radi8tor #105307 üzenetére

  lehet nem végleges, de van akinek 8 hónap után sem jött vissza:
  Clinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis
  
  We evaluated 97 patients (67 women [69.1%]; mean [SD] age, 38.8 [11.5] years) with acute smell loss beyond 7 days.
  ...
  After subjective assessment at 4 months, 23 of 51 patients (45.1%) reported full recovery of olfaction, 27 of 51 patients (52.9%) reported partial recovery, and 1 of 51 patients (2.0%) reported no recovery. On psychophysical testing, 43 of 51 patients (84.3%) were objectively normosmic, including 19 of 27 (70.0%) who self-evaluated as only partially recovered (all patients who self-reported normal return of smell were corroborated with objective testing) (Table). The remaining 8 patients (15.7%) with persistent subjective or objective loss of smell were followed up at 8 months, and an additional 6 patients became normosmic on objective testing. At 8 months, objective olfactory assessment confirmed full recovery in 49 of 51 patients (96.1%). Two patients remained hyposmic at 1 year, with persistent abnormalities (1 with abnormal olfactory threshold and 1 with parosmia causing abnormal identification). Among those who underwent subjective assessment alone, 13 of 46 patients (28.2%) reported satisfactory recovery at 4 months (7 with total and 6 with partial recovery), and the remaining 33 patients (71.7%) did so by 12 months (32 with total and 14 with partial recovery).
  
  More than 1 year into the pandemic, we describe the long-term prognosis for a cohort of patients with COVID-19–related anosmia, most of whom (96.1%) objectively recovered by 12 months. Our findings suggest that an additional 10% gain in recovery can be expected at 12 months, compared with studies with 6 months of follow-up that found only 85.9% of patients with recovery.4 This supports findings from fundamental animal research, involving both imaging studies and postmortem pathology, suggesting that COVID-19–related anosmia is likely due to peripheral inflammation.4

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